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Zach Adelman

Adelman, Zach
Zach Adelman
Professor, Texas A&M AgriLife Research Fellow, Texas A&M University Presidential Impact Fellow
Office:
Heep Center 329A
Email:
Phone:
979-458-3107
https://entomology.tamu.edu/zach-adelman-lab/
Undergraduate Education
B.A. Ithaca College - 1996
Graduate Education
Ph.D. Colorado State University - 2000

Publications

  1. Adelman, Z. N. and Tu, Z. (2016) Control of mosquito-borne infectious diseases: Sex and gene drive. Trends in Parasitology. Mar;32(3):219-29.
    Press: Phys.org, The Guardian, Healthline, Infectious Disease News
  1. Benoit, J. B., Adelman, Z. N., Reinhardt, K., Dolan, A, Poelchau, M., et al (2016) Unique features of the bed bug, a global human ectoparasite, identified through genome sequencing. Nat Commun.Feb 2;7:10165.
    Press: The Verge, Chicago Tribune, Newsweek, Discovery News, Science News
  1. Hall, A. B., Basu, S. Jiang, X., Qi, Y., Timoshevskiy, V. A., Biedler, J. K., Sharakhova, M. V., Elahi, R., Anderson, M. A. E., Chen, X., Sharakhov, I. V., Adelman, Z. N., and Zhijian Tu. (2015) A male determining factor in the mosquito Aedes aegypti. Science. 348 (6240):1268-70
    Press: Science_Mag_Blog, The Verge, SlashDot, Phys.org, Io9, Quartz, WVTF (NPR Blacksburg/Roanoke), MedicalDaily, KPCC (NPR Southern California)
  1. Haac, M. E., Anderson, M. A. E., Eggleston, H., Myles, K. M., and Adelman, Z. N. (2015) The hub protein Loquacious connects the microRNA and short interfering RNA pathways in mosquitoes.Nuc. Acids. Res. 43(7):3688-700
  1. Basu, S., Aryan, A., Overcash, J. M., Samuel, G.H., Anderson, M. A. E., Dahlem, T., Myles, K. M., and Adelman, Z. N. (2015) Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti. Proc Natl Acad Sci USA 112(13):4038-43.
    Press: Genetic Engineering & Biotechnology News, NPR
  1. Overcash, J. M., Aryan, A., Myles, K. M., and Adelman, Z.N. (2015) Understanding the DNA damage response in order to achieve desired gene editing outcomes in mosquitoes. Chromosome Research. 23(1):31-42
  1. O’Neal S. T., Samuel, G. H., Adelman, Z. N., and Myles, K. M. (2014) Suppressors of invertebrate antiviral RNA silencing and mosquito-borne viruses. Viruses. (6): 4314-4331.
  1. Liu, M., Adelman, Z. N., Myles, K. M., and Zhang, L. (2014) TransPS: A transcriptome post scaffolding method for assembling high quality contigs. Computational Biology Journal. Volume 2014, Article ID 961823
  1. Aryan, A., Myles, K. M., Adelman, Z. N. (2014) Targeted genome editing in Aedes aegypti using TALENs. Methods. (69): 38-45.
  1. Allen, W. J., Wiley, M. R., Myles, K. M., Adelman, Z. N., Bevan, D. R. (2014) Steered Molecular Dynamics Identifies Critical Residues of the Nodamura Virus B2 Suppressor of RNAi. J. Mol. Mod. 20:2092
  1. Hall, A. B., Timoshevskiy, V. A., Sharakhova, M. V., Jiang, X., Basu, S., Anderson, M. A. E., Hu, W., Sharakhov, I. V., Adelman, Z. N., and Tu, Z. (2014). Insights into the preservation of the homomorphic sex-determining chromosome of Aedes aegypti from the discovery of a male-biased gene tightly-linked to the M-locus. Genome Biol. Evol. 6(1): 179-191.
  1. Adelman, Z. N., Miller, D. M., and Myles, K. M. (2013) Bed bugs and infectious disease; a case for the arboviruses. PLoS Path. 9(8): e1003462. Comment: Nominated for F1000.
  1. Koganemaru, R., Miller, D. M., and Adelman, Z. N. (2013) Robust cuticular penetration resistance in the common bed bug (Cimex lectularius L.) correlates with increased steady-state transcript levels of CPR- type cuticle protein genes. Pest. Biochem. Phys. (106): 190-197.
  1. Adelman, Z. N., Anderson, M. A. E., Wiley, M. R., Murreddu, M., Samuel, H., Morazzani, E. M, and Myles, K. M. (2013) Cooler temperatures destabilize RNA interference and increase susceptibility of disease vector mosquitoes to viral infection. PLoS Neg. Trop. Dis. 7(5): e2239.
  1. Aryan, A., Anderson, M. A. E., Myles, K. M., and Adelman, Z. N. (2013) Germline excision of transgenes in Aedes aegypti by homing endonucleases. Sci. Rep. (3): 1603.
  1. Aryan, A., Anderson, M. A. E., Myles, K. M., and Adelman Z. N. (2013) TALEN-based gene disruption in the dengue vector Aedes aegypti. PLoS One 8 (3): e60082.
    Press: NBC news; Biotechniques, Oxbridge Biotech.
  1. Adelman, Z. N., Anderson, M. A. E., Liu, M., Zhang, L., and Myles, K. M. (2012) Sindbis virus induces the production of a novel class of endogenous siRNAs in Aedes aegypti mosquitoes Insect Mol. Bio. 21(3), 357–368.
  1. Carpenetti, T. L. G., Aryan, A., Myles, K. M., and Adelman, Z. N. (2012) Robust heat-inducible gene expression by two endogenous hsp70-derived promoters in transgenic Aedes aegypti. Insect. Mol. Bio. 21(1), 97-106.
  1. Morrazzani, E. M., Wiley, M. R., Murreddu, M., Adelman, Z. N., and Myles, K. M. (2012) Production of Virus-Derived Ping-Pong-Dependent piRNA-like small RNAs in the Mosquito Soma. PLoS Path. 8(1): e1002470.
  1. Adelman, Z. N., Kilcullen, K. A., Koganemaru, R., Anderson, M. A. E., Anderson, T. D., and Miller, D. M. (2011) Deep sequencing of pyrethroid-resistant bed bugs reveals multiple mechanisms of resistance within a single population. PLoS One 6(10): e26228.Press: Popular Mechanics
  1. Phoutrides E. K., Coulibaly M. B., George C. M., Sacko A., Traore S., Bessoff K., Wiley M. R., Kolivras K. N., Adelman Z., Traore M., Hunsperger E. A. (2011) Dengue Virus Seroprevalence Among Febrile Patients in Bamako, Mali: Results of a 2006 Surveillance Study. Vector Borne Zoonotic Dis. 11(11): 1479-1485.
  1. Davis, G.A., Havill, N.P., Adelman, Z.N., Caccone, A., Kok, L.T., Salom, S.M. (2011) DNA barcodes and molecular diagnostics to distinguish an introduced and native Laricobius(Coleoptera:Derodontidae) species in eastern North America. Biol. Control 58, pp53-59.
  1. Wiley, M. R., Roberts, L. O., Adelman, Z. N., and Myles, K. M. (2010) Double-subgenomic alphaviruses expressing multiple fluorescent proteins using a Rhopalosiphum padi virus internal ribosome entry site element. PLoS ONE 5(11): e13924, 1-8.
  1. Anderson, M. A. E., Gross, T. L., Myles, K. M., and Adelman, Z. N. (2010) Validation of novel promoter sequences derived from two endogenous ubiquitin genes in transgenic Aedes aegypti. Insect Mol Bio 19 (4), 441-449.
  1. Plaskon, N. E., Adelman, Z. N., and Myles K. M. (2009). Accurate strand-specific quantification of viral RNA. PLoS ONE 4 (10), e7468, 1-8.
  1. Traver, B., Anderson, M. A. E., and Adelman, Z. N. (2009). Homing endonucleases catalyze double- stranded DNA breaks and somatic transgene excision in Aedes aegypti. Insect Mol. Bio. 18 (5), 623- 633.
  1. Myles, K. M., Morazzani, E. M. and Adelman, Z. N. (2009) Origins of virus-derived small RNAs in mosquitoes. RNA Biol 6 (4), 387-391.
  1. Gross T. L., Myles K. M., and Adelman, Z. N. (2009). Identification and characterization of heat shock 70 genes in the yellow fever mosquito, Aedes aegypti. J Med Ento 46 (3), 496-504.
  1. Myles, K. M., M. R. Wiley, E. M. Morazzani, and Adelman, Z. N. (2008). Alphavirus-derived small RNAs modulate pathogenesis in disease vector mosquitoes. Proc Natl Acad Sci USA 105 (50), 19938-43. Comment: Nominated for F1000. Press: Scientific American.
  1. Adelman, Z. N., Anderson, M. A. E., Morazzani, E. M., and Myles, K. M. (2008). A transgenic sensor strain for monitoring the RNAi pathway in the yellow fever mosquito, Aedes aegypti. Insect Biochem Mol Biol 38 (7), 705-713.
  1. Adelman, Z. N., Jasinskiene, N., Onal, S., Juhn, J., Ashikyan, A., Salampessy, M., Macauley, T., and James, A.A. (2007) nanos gene control DNA mediates developmentally-regulated transposition in the yellow fever mosquito, Aedes aegypti. Proc Natl Acad Sci USA 104 (24), 9970-9975.
  1. Franz, A. W., Sanchez-Vargas, I., Adelman, Z. N., Blair, C. D., Beaty, B. J., James, A. A., and Olson, K. E. (2006). Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti. Proc Natl Acad Sci USA 103 (11), 4198-203.
  1. Calvo, E., Walter, M., Adelman, Z. N., Jimenez, A., Onal, S., Marinotti, O., and James, A. A. (2005). Nanos (nos) genes of the vector mosquitoes, Anopheles gambiae, Anopheles stephensi and Aedes aegypti. Insect Biochem Mol Biol 35 (7), 789-98.
  1. Adelman, Z.N., Jasinskiene, N., Vally, K.J.M., Peek, C., Travanty, E.A., Olson K.E., Brown, S.E., Stephens, J.L., Knudson D.L., Coates C.J., and James, A.A. (2004). Formation and loss of large, unstable tandem arrays of the piggyBac transposable element in the yellow fever mosquito, Aedes aegypti. Transgenic Research 13, 411-425.
  1. Travanty, E. A., Adelman, Z. N., Franz, A. W., Keene, K. M., Beaty, B. J., Blair, C. D., James, A. A., and Olson, K. E. (2004) Using RNA interference to develop dengue virus resistance in genetically modified Aedes aegypti. Insect Biochem Mol Biol 34 (7) 607-613.
  1. Adelman Z. N., Sanchez-Vargas I., Travanty, E. A., Carlson, J. O., Beaty, B. J., Blair C. D., Olson K. E. (2002) RNA silencing of dengue virus type 2 replication in transformed C6/36 mosquito cells transcribing an inverted repeat RNA derived from the virus genome. J. of Virology 76 (24), 12925- 12933.
  1. Olson, K. E., Adelman, Z. N., Travanty, E. A., Sanchez-Vargas, I., Beaty, B. J., Blair, C. D. (2002) Developing arbovirus resistance in mosquitoes. Insect Biochem. Mol. Bio. 32, 1333-1343.
  1. Adelman, Z. N., Jasinskiene, N., James, A. A. (2002) Development and applications of transgenesis in the yellow fever mosquito, Aedes aegypti. Mol. Biochem. Parisitol. 121 (1), 1-10.
  1. Adelman Z. N., Carlson J. O., Beaty B. J., Blair C. D., Olson K. E. (2001) Sindbis virus-induced gene silencing of dengue viruses in mosquitoes. Insect. Mol. Biol. Vol 10 (3), 265-73.
  1. Shiao S. H., Higgs, S., Adelman Z., Christensen B. M., Liu S. H., Chen C. C. (2001) Effect of prophenoloxidase expression knockout on the melanization of microfilariae in the mosquito Armigeres subalbatus. Insect Mol. Biol. Vol 10 (4), 315-321.
  1. Blair C. D., Adelman Z. N., Olson K. E. (2000). Molecular strategies for interrupting arthropod-borne virus transmission by mosquitoes. Clin. Micro. Rev. 13 (4), 651-661.
  1. Golub R., Adelman Z., Clementi J., Weiss R., Bonasera J., Servetnick M. (2000). Evolutionarily conserved and divergent expression of members of the FGF receptor family among vertebrate embryos, as revealed by FGFR expression patterns in Xenopus. Dev. Genes Evol. 210, 345-357.