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Kevin Myles

Myles, Kevin
Kevin Myles
Heep Center 329B
Undergraduate Education
B.S. Microbiology - Colorado State University
Graduate Education
Ph.D. Microbiology - Colorado State University

Professional Summary

Kevin Myles is currently Professor of Entomology at Texas A & M University (TAMU). He earned his Ph.D. in Microbiology from Colorado State University in 2002, working under Professors Barry Beaty, a member of the prestigious National Academy of Sciences, Ken Olson and Carol Blair at the Arthropod Infectious Disease Laboratories (AIDL). After completing his Ph.D., Kevin was awarded a postdoctoral research fellowship by the American Society for Microbiology (ASM) and National Center for Infectious Diseases (NCID), which he served at the Centers for Disease Control and Prevention (CDC), Division of Vector-borne Infectious Diseases, under Dr. Ann Powers. In 2005, Kevin accepted an Assistant Professor position at Virginia Tech University, where he remained until moving to TAMU in 2016. Projects in his laboratory focus on understanding the role of invertebrate antiviral immune pathways in the transmission of mosquito-borne viruses. Kevin’s multidisciplinary approach to this research area has resulted in several key discoveries regarding antiviral immunity in disease vector mosquitoes.

Research Areas of Expertise

My laboratory employs a multi-disciplinary approach involving genetics, molecular virology, next-generation sequencing, bioinformatics, and gene editing to better understand the biology of mosquitoes and the virus pathogens that they transmit to human and animal hosts. We place a particular emphasis on the identification of information that can be used to disrupt the transmission of mosquito-borne viruses.

Selected Publications

Samuel GH, Adelman ZN, Myles KM (2018) Antiviral Immunity and Virus-Mediated Antagonism in Disease Vector Mosquitoes. Trends Microbiol 26(5):447-461.

Samuel GH, Wiley MR, Badawi A, Adelman ZN and Myles KM (2016) Yellow fever virus capsid protein is a potent suppressor of RNA silencing that binds double-stranded RNA. Proc Natl Acad Sci USA 113(48): 13863-68.

Basu S, Aryan A, Overcash JM, Samuel GH, Anderson MA, Dahlem TJ, Myles KM, Adelman ZN (2015) Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti. Proc Natl Acad Sci USA 112(13): 4038-43

Morazzani EM, Wiley MR, Murreddu MG, Adelman ZN, Myles KM (2012) Production of Virus-Derived Ping-Pong-Dependent piRNA-like Small RNAs in the Mosquito Soma. PLoS Pathog 8: 1-11 e1002470 Myles KM, Wiley MR, Morazzani EM, and Adelman ZN. (2008). Alphavirus-derived small RNAs modulate pathogenesis in disease vector mosquitoes. Proc Natl Acad Sci USA 105: 19938-19943.